{"title":"Longevity \u0026 Mitochondrial","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif;\"\u003eThis collection brings together the best peptides for longevity research in our Canadian catalog — compounds with documented activity across mitochondrial bioenergetics, cellular signaling, and age-associated metabolic decline.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"mots-c-research-peptide-canada","title":"MOTS-c","description":"\u003ch2\u003e\n\u003cmeta charset=\"utf-8\"\u003eMOTS-c Research Peptide Canada: Mitochondrial-Derived Peptide\u003c\/h2\u003e\n\u003cp\u003eMOTS-c is a mitochondrial-derived peptide — a short, 16-amino-acid sequence encoded within mitochondrial DNA. Groups sourcing the MOTS-c research peptide in Canada are typically investigating mitochondrial signalling and metabolic regulation.\u003c\/p\u003e\n\u003cp\u003eMechanistically, MOTS-c is studied for its association with the AMPK pathway and with cellular responses to metabolic stress, making it a tool of interest in mitochondrial and metabolic research.\u003c\/p\u003e\n\u003ch2\u003e\u003cb\u003eProduct Details\u003c\/b\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eForm:\u003c\/b\u003e Lyophilized peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eNet per vial:\u003c\/b\u003e 10 mg (filled to approximately 104% of label)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e ≥99% (HPLC-verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eIdentity:\u003c\/b\u003e MS-verified (per COA)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e 2–8 °C, protect from light\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFormula \/ M.W.:\u003c\/b\u003e C₁₀₁H₁₅₂N₂₈O₂₂S₂ \/ 2174.64 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eCAS:\u003c\/b\u003e 1627580-64-6\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat Makes MOTS-c a Unique Research Compound\u003c\/h2\u003e\n\u003cp\u003eMOTS-c belongs to a small, distinctive class: peptides encoded not in the nuclear genome but within the mitochondrial 12S rRNA region. It was identified around 2015 by Lee, Cohen, and colleagues, and its discovery helped establish the idea that mitochondria themselves can produce signalling peptides.\u003c\/p\u003e\n\u003cp\u003eIn research terms, MOTS-c is examined for its influence on metabolic homeostasis, with the AMPK pathway frequently central to the proposed mechanism. Investigators are drawn to it because it links mitochondrial state to whole-cell metabolic signalling — a connection few other tool compounds capture as directly.\u003c\/p\u003e\n\u003cp\u003eAgainst adjacent metabolic peptides, MOTS-c is unusual in originating from the mitochondrial genome, which is why it recurs in Canadian research on mitochondrial regulation and metabolic stress responses.\u003c\/p\u003e\n\u003ch2\u003eResearch Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Regulation —\u003c\/strong\u003e MOTS-c is studied for its association with glucose and energy metabolism via AMPK signalling in cellular models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Research —\u003c\/strong\u003e As a mitochondrial-derived peptide, it is a tool for probing mitochondria-to-cell communication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Stress Response —\u003c\/strong\u003e Research examines its role in how cells respond to metabolic and oxidative stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAging \u0026amp; Longevity Research —\u003c\/strong\u003e It appears in study panels investigating metabolic contributors to cellular aging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated Peptides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSS-31\u003c\/strong\u003e — A mitochondria-targeting peptide studied in overlapping research areas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+\u003c\/strong\u003e — A coenzyme examined in cellular-metabolism and longevity research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMito Stack\u003c\/strong\u003e — A proprietary blend within the mitochondrial research domain.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eIs the MOTS-c research peptide available in Canada?\u003c\/strong\u003e Yes. MOTS-c is supplied to Canadian research buyers as a lyophilized, research-grade peptide, HPLC-verified to ≥99% with MS-confirmed identity and a batch-specific COA.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is MOTS-c different from SS-31?\u003c\/strong\u003e Both relate to mitochondrial research, but MOTS-c is a mitochondrial-derived signalling peptide studied via AMPK and metabolic pathways, whereas SS-31 is a synthetic peptide studied for targeting and stabilising the inner mitochondrial membrane.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs MOTS-c naturally occurring?\u003c\/strong\u003e The sequence is encoded within mitochondrial DNA, so it has a natural counterpart; the supplied material is a synthesised research-grade version.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow are purity and identity verified?\u003c\/strong\u003e Each batch is HPLC-verified (≥99%) and MS-confirmed, with a batch-specific COA. Material is lyophilized and stored at 2–8 °C, protected from light.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e⚠️ \u003c\/strong\u003e\u003cem\u003eFor research use only. Not intended for human or veterinary use. Not a drug, food, or supplement.\u003c\/em\u003e\u003c\/p\u003e","brand":"Reta Labs","offers":[{"title":"10mg","offer_id":55144805007652,"sku":null,"price":59.99,"currency_code":"CAD","in_stock":true},{"title":"6 x 10mg","offer_id":55144805040420,"sku":null,"price":319.99,"currency_code":"CAD","in_stock":true},{"title":"10 x 10mg (one box)","offer_id":55144805073188,"sku":null,"price":499.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1012\/4424\/0164\/files\/Mots-c-retalabs.png?v=1781996155"},{"product_id":"buy-ss-31-canada","title":"SS-31","description":"\u003cp\u003eSS-31 (elamipretide) is a synthetic, mitochondria-targeting tetrapeptide. Research groups who buy SS-31 in Canada are typically studying mitochondrial membrane function and cellular bioenergetics.\u003c\/p\u003e\n\u003cp\u003eMechanistically, SS-31 is investigated for its association with cardiolipin on the inner mitochondrial membrane and the resulting influence on mitochondrial structure and energy production.\u003c\/p\u003e\n\u003ch2\u003e\u003cb\u003eProduct Details\u003c\/b\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eForm:\u003c\/b\u003e Lyophilized peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eNet per vial:\u003c\/b\u003e 10 mg (filled to approximately 104% of label)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e ≥99% (HPLC-verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eIdentity:\u003c\/b\u003e MS-verified (per COA)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e 2–8 °C, protect from light\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFormula \/ M.W.:\u003c\/b\u003e C₃₂H₄₉N₉O₅ \/ 639.8 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eCAS:\u003c\/b\u003e 736992-21-5\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat Makes SS-31 a Unique Research Compound\u003c\/h2\u003e\n\u003cp\u003eSS-31 belongs to a class of small, cell-permeable peptides designed to localise to mitochondria — specifically to associate with cardiolipin, a lipid concentrated in the inner mitochondrial membrane. That targeting is what distinguishes it from broadly acting metabolic tools.\u003c\/p\u003e\n\u003cp\u003eIn the research literature, SS-31 is examined for its influence on mitochondrial membrane integrity and bioenergetic efficiency, with cardiolipin interaction central to the proposed mechanism. Researchers value its specificity for the organelle.\u003c\/p\u003e\n\u003cp\u003eCompared with mitochondrial-derived peptides like MOTS-c, SS-31's research emphasis is structural — the membrane itself — rather than signalling, which is why the two are often studied together to address complementary mitochondrial questions in Canadian research.\u003c\/p\u003e\n\u003ch2\u003eResearch Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Membrane Research —\u003c\/strong\u003e SS-31 is studied for its association with cardiolipin and inner-membrane integrity in models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioenergetics —\u003c\/strong\u003e The literature examines its relationship to mitochondrial energy-production efficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative-Stress Research —\u003c\/strong\u003e Research investigates its role in models of mitochondrial oxidative stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative Mitochondrial Studies —\u003c\/strong\u003e It is used alongside MOTS-c as a structural-focus tool.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated Peptides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"https:\/\/retalabs.ca\/products\/mots-c-research-peptide-canada\" target=\"_blank\" title=\"View MOTS-c Product Page\" rel=\"noopener\"\u003eMOTS-c\u003c\/a\u003e\u003c\/strong\u003e — A mitochondrial-derived signalling peptide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+\u003c\/strong\u003e — A coenzyme studied in cellular-energy research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/retalabs.ca\/products\/tissue-repair-peptide-stack-canada\" target=\"_blank\" title=\"View Wolverine Stack Product Page\" rel=\"noopener\"\u003e\u003cstrong\u003eWolverine Stack\u003c\/strong\u003e\u003c\/a\u003e — A proprietary healing \u0026amp; recovery research blend.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eWhere can I buy SS-31 in Canada for research?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSS-31 is supplied to Canadian research buyers as a lyophilized, research-grade peptide, HPLC-verified to ≥99% with MS-confirmed identity and a batch-specific COA.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow is SS-31 different from MOTS-c?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSS-31 is a synthetic peptide studied for targeting and stabilising the inner mitochondrial membrane via cardiolipin, whereas MOTS-c is a mitochondrial-derived peptide studied through AMPK and metabolic signalling.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs SS-31 naturally occurring?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNo. It is a synthetic, mitochondria-targeting tetrapeptide developed for research.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow are purity and identity verified?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eEach batch is HPLC-verified (≥99%) and MS-confirmed, with a batch-specific COA. Material is lyophilized and stored at 2–8 °C, protected from light.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e⚠️ \u003c\/strong\u003e\u003cem\u003eFor research use only. Not intended for human or veterinary use. Not a drug, food, or supplement.\u003c\/em\u003e\u003c\/p\u003e","brand":"Reta Labs","offers":[{"title":"10mg","offer_id":55370524262692,"sku":null,"price":59.99,"currency_code":"CAD","in_stock":false},{"title":"6 x 10mg","offer_id":55370524295460,"sku":null,"price":329.99,"currency_code":"CAD","in_stock":false},{"title":"10 x 10mg (one box)","offer_id":55370524328228,"sku":null,"price":499.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1012\/4424\/0164\/files\/ss31_retalabs.png?v=1782695841"},{"product_id":"buy-nad-plus-canada","title":"NAD+","description":"\u003cp\u003eNAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular energy metabolism. Research groups who buy NAD+ in Canada are typically studying redox reactions, metabolism, and cellular-aging pathways.\u003c\/p\u003e\n\u003cp\u003eMechanistically, NAD+ is investigated for its role as an electron carrier in metabolic reactions and as a substrate for enzymes involved in cellular signalling and repair.\u003c\/p\u003e\n\u003ch2\u003e\u003cb\u003eProduct Details\u003c\/b\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eForm:\u003c\/b\u003e Lyophilized free acid\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eNet per vial:\u003c\/b\u003e 600 mg (filled to approximately 104% of label)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e ≥99% (HPLC-verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eIdentity:\u003c\/b\u003e MS-verified (per COA)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e 2–8 °C, protect from light; long-term storage at −20 °C\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eFormula \/ M.W.:\u003c\/b\u003e C₂₁H₂₇N₇O₁₄P₂ \/ 663.43 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eCAS:\u003c\/b\u003e 53-84-9\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat Makes NAD+ a Unique Research Compound\u003c\/h2\u003e\n\u003cp\u003eNAD+ differs from the peptides in the Reta Labs catalogue: it is a coenzyme rather than a peptide, but it is a foundational research material in metabolism and aging studies. Its central role as an electron carrier places it at the heart of cellular energy production.\u003c\/p\u003e\n\u003cp\u003eIn the literature, NAD+ is examined both as a metabolic cofactor and as a substrate for enzyme families — such as sirtuins and PARPs — implicated in cellular signalling, DNA repair, and aging. That breadth makes it a recurring reference in mitochondrial and longevity research.\u003c\/p\u003e\n\u003cp\u003eWithin Canadian research, NAD+ is frequently sourced alongside mitochondrial peptides such as MOTS-c because the questions overlap: how cellular-energy status relates to signalling, repair, and aging.\u003c\/p\u003e\n\u003ch2\u003eResearch Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Energy Metabolism —\u003c\/strong\u003e NAD+ is studied as a central electron carrier in metabolic-pathway research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRedox Research —\u003c\/strong\u003e It serves as a tool for studying cellular redox balance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAging \u0026amp; Longevity Research —\u003c\/strong\u003e The literature examines its relationship to sirtuin- and repair-enzyme activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnzyme-Substrate Studies —\u003c\/strong\u003e It is used as a substrate in research on NAD-consuming enzymes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRelated Peptides\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"https:\/\/retalabs.ca\/products\/mots-c-research-peptide-canada\" target=\"_blank\" title=\"View MOTS-c Product Page\" rel=\"noopener\"\u003eMOTS-c\u003c\/a\u003e\u003c\/strong\u003e — A mitochondrial-derived peptide studied in metabolic contexts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"https:\/\/retalabs.ca\/products\/buy-ss-31-canada\" target=\"_blank\" title=\"View SS-31 Product Page\" rel=\"noopener\"\u003eSS-31\u003c\/a\u003e\u003c\/strong\u003e — A mitochondria-targeting peptide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003ca href=\"https:\/\/retalabs.ca\/products\/tissue-repair-peptide-stack-canada\" target=\"_blank\" title=\"View Wolverine Stack Product Page\" rel=\"noopener\"\u003eWolverine Stack\u003c\/a\u003e\u003c\/strong\u003e — A proprietary healing \u0026amp; recovery research blend.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eWhere can I buy NAD+ in Canada for research?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNAD+ is supplied to Canadian research buyers as a lyophilized, research-grade material, HPLC-verified to ≥99% with MS-confirmed identity and a batch-specific COA.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs NAD+ a peptide?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eNo. NAD+ is a coenzyme (a dinucleotide), not a peptide, but it is a core research material in metabolism and aging studies, which is why it sits within the metabolic research cluster.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIs NAD+ naturally occurring?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eYes — NAD+ occurs in all living cells. The supplied material is a synthesised, research-grade form.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow are purity and identity verified?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eEach batch is HPLC-verified (≥99%) and MS-confirmed, with a batch-specific COA. Material is lyophilized and stored at 2–8 °C, protected from light.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e⚠️\u003c\/strong\u003e\u003cem\u003e For research use only. Not intended for human or veterinary use. Not a drug, food, or supplement.\u003c\/em\u003e\u003c\/p\u003e","brand":"Reta Labs","offers":[{"title":"600mg","offer_id":55370542088484,"sku":null,"price":109.99,"currency_code":"CAD","in_stock":false},{"title":"6 x 600mg","offer_id":55370542121252,"sku":null,"price":599.99,"currency_code":"CAD","in_stock":false},{"title":"10 x 600mg (one box)","offer_id":55370542154020,"sku":null,"price":849.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1012\/4424\/0164\/files\/NAD__retalabs.png?v=1782696150"}],"url":"https:\/\/retalabs.ca\/collections\/best-peptides-for-longevity.oembed","provider":"Reta Labs","version":"1.0","type":"link"}