GHK-Cu

• Form: Lyophilized peptide complex
• Net per vial: 50 mg (filled to approximately 104% of label)
• Purity: ≥99% (HPLC-verified)
• Identity: MS-verified (per COA)
• Storage: 2–8 °C, protect from light
• Formula / M.W.: C₁₄H₂₃CuN₆O₄ / ~401.91 Da
• CAS: 49557-75-7

GHK-Cu was first characterised by Loren Pickart in the early 1970s, identified as a copper-binding tripeptide present in human plasma whose levels change with age. That natural origin and copper-carrying role set it apart from purely synthetic tool peptides.

In the research literature, GHK-Cu is examined for its influence on extracellular-matrix remodelling and on the expression of genes associated with repair, making it a long-standing tool in skin- and wound-research models. Its copper complex is central to the proposed mechanisms.

Compared with adjacent repair peptides, GHK-Cu is distinctive for combining a defined metal-ion role with remodelling activity, which is why it recurs in Canadian skin- and tissue-research designs and anchors the pigmentation-and-skin cluster alongside BPC-157 in repair panels.

• Tissue Remodeling — GHK-Cu is studied for its association with extracellular-matrix remodelling in laboratory models.
• Skin Research — The literature examines its role in skin- and wound-research designs.
• Gene-Expression Research — Research investigates its influence on remodelling- and repair-related gene activity.
• Copper-Transport Studies — As a copper-binding peptide, it is a tool for studying metal-ion delivery.
• Antioxidant-Pathway Research — Its copper complex is examined in research on cellular antioxidant systems.

Researchers working with GHK-Cu often investigate it alongside:

• BPC-157 — A repair-focused peptide studied in adjacent remodelling contexts.
• TB-500 — A thymosin-derived peptide studied in repair models.
• Glow Stack — A proprietary blend within the skin/pigmentation research domain.

Where can I buy GHK-Cu in Canada for research?

GHK-Cu is supplied to Canadian research buyers as a lyophilized, research-grade peptide, HPLC-verified to ≥99% with MS-confirmed identity and a batch-specific COA.

How is GHK-Cu different from other repair peptides?

GHK-Cu is a copper-binding tripeptide of natural origin studied for matrix-remodelling and gene-expression effects, distinct from peptides like BPC-157 or TB-500 that are studied through angiogenesis and cell-migration mechanisms.

Is GHK-Cu naturally occurring?

Yes — it occurs naturally in human plasma. The supplied material is a synthesised, research-grade copper-complexed version.

Why is the copper complex important?

The copper ion is central to GHK-Cu's proposed mechanisms in the literature, which is why it is studied as a copper-complexed tripeptide rather than as the bare peptide sequence.